Raman spectroscopy - advanced optical analysis technology
Boost plant safety, ensure product quality, and optimize operations. Raman spectroscopy measures the composition and molecular structure of your samples from lab-to-process in real time.
Specs at a glance
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Wetted materials
Body: 316L stainless steel
Window: Proprietary material, optimized for bioprocesses
Process connection: PG13.5 for industry standard sensor housings, welded port connectors available
Surface finish: Ra 15 with electropolish
Adhesive: USP Class VI and ISO993 compatible -
Sterilization method
CIP/SIP
Field of application
The Raman Rxn-45 probe capitalizes on the power of Raman in bioprocess manufacturing by measuring multiple, specific components in real-time for continuous, around-the-clock process feedback. It also meets the daunting sampling requirements of compliance, sterilization, port compatibility, and convenience. The Raman Rxn-45 probe was designed for installation in development and cGMP stainless-steel reactors and is successfully used to provide an analytical “eye” into large-scale bioprocesses.
Cell culture: glucose, lactate, amino acids, cell density, titer, and more
Fermentation: glucose, glycerol, acetate, methanol, ethanol, biomass, and more
Benefits
Measures multiple components in real-time for automated 24/7 process feedback
Provides long-term measurement stability
Offers a suitable surface finish for cGMP manufacturing
Provides compatibility with industry standard bioreactor side ports and sensor housings
Offers the flexibility of being installed in development and production reactors
Reduces sterilization and cleaning burdens with CIP/SIP standard compatibility
Extended selection
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High-end products
- Highly functional and convenient
Technical excellence
Simplicity
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Standard products
- Reliable, robust and low-maintenance
Technical excellence
Simplicity
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Specialized products
- Designed for demanding applications
Technical excellence
Simplicity
Variable
| FLEX selections | Technical excellence | Simplicity |
|---|---|---|
Fundamental selection Meet your basic measurement needs |
Technical excellence
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Simplicity
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Lean selection Handle your core processes easily |
Technical excellence
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Simplicity
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Extended selection Optimize your processes with innovative technologies |
Technical excellence
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Simplicity
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Xpert selection Master your most challenging applications |
Technical excellence
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Simplicity
Variable |
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Success stories
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Most downloaded
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Technical Information (TI)
Rxn-45 Raman Spectroscopic Probe Technical Information
English version - 08/2022
System design and specifications for the Raman Rxn-45 probe
Language:
English
Version:
03/08/2022
File size:
308.3 KB
File name:
TI01633CEN_0222.pdf
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28 documents
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Technical Information (TI)
Rxn-45 Raman Spectroscopic Probe Technical Information
System design and specifications for the Raman Rxn-45 probe
Language:
English
Version:
03/08/2022
File size:
308.3 KB
File name:
TI01633CEN_0222.pdf
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Operating Instruction (BA)
Rxn-45 Raman Spectroscopic Probe Operating Instructions
Commissioning, operation, and maintenance details
for the Raman Rxn-45 probeLanguage:
English
Version:
03/08/2022
File size:
781.1 KB
File name:
BA02169CEN_0222.pdf
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Short Instruction (KA)
Rxn-45 Raman Spectroscopic Probe Brief Operating Instructions
Quick start guide for the Raman Rxn-45 probe
Language:
English
Version:
03/08/2022
File size:
504.6 KB
File name:
KA01549CEN_0222.pdf
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PU (Publication)
Endress+Hauser - your one-source Life Sciences technology partner
Graphic highlighting why Endress+Hauser is trusted by the
world's top biopharmaceutical manufacturers for its Life
Sciences expertise and reliable inline, real-time measurement
technologies like Raman spectroscopy systems (Raman Rxn2,
Raman Rxn4, Rxn-10, Rxn-45, Rxn-46, bio multi optic and sleeve,
flow cell and flow bench, Raman optic system for single use) and
liquid analysis sensor technology (Liquiline CM44P, CM442 and
OUSAF44, OUSBT66 and Memosens CPS61E, CLS82E, COS81E,
CLS82E).Language:
English
Version:
27/06/2024
File size:
1.9 MB
File name:
PU01585CEN_0124.pdf
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PU (Publication)
Advanced process and product control in fermentations - Raman spectroscopy for composition analysis in a lab or process
An overview of Raman spectroscopy analyzer systems (including the
Raman Rxn2 analyzer, Raman Rxn4 analyzer, Rxn-10 probe, and Rxn-45
probe), powered by Kaiser Raman technology, for fermentation
compositional analysis in a lab or process applicable to biotechnology
in the food & beverage industry.Language:
English
Version:
03/03/2022
File size:
603 KB
File name:
PU01457CEN_0122.pdf
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PU (Publication)
Raman application guide for the life science industry - Trusted composition analysis for the life sciences
A guide to our Raman spectroscopy application notes for the
Life Science industry (featuring the Raman Rxn2 analyzer,
Raman Rxn4 analyzer, Rxn-10 probe, Rxn-20 probe, Rxn-45 probe,
Rxn-46 probe, and probe accessory optics (bIO-Optic, Raman single
use optic system / SUB, immersion optic, non-contact optic).Language:
English
Version:
19/04/2022
File size:
1.1 MB
File name:
PU01447CEN_0222.pdf
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PU (Publication)
ライフサイエンス産業向けのラマンアプリケーションガイド -ライフサイエンスのための信頼できる組成分析
ライフサイエンス産業向けラマン分光法アプリケーションノート（ラマンRxn2アナライザー、ラマンRxn4アナライザー、Rxn-10プローブ、
Rxn-20プローブ、Rxn-45プローブ、Rxn-46プローブ、プローブオプティックアクセサリ（bIOオプティック、シングルユース向け
ラマンオプティックシステム/SUB、浸漬オプティック、非接触オプティック）.Language:
Japanese
Version:
02/08/2024
File size:
1.4 MB
File name:
PU01447CJA_0222_Raman_App_Guide_for_LifeScience.pdf
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PU (Publication)
Prioritize scalability for an efficient biopharmaceutical product development lifecycle
This technical paper studies the importance of scalability as a
competitive advantage in bioprocessing in the Life Science industry,
and Endress+Hauser's scalable Raman systems (Raman Rxn2,
Raman Rxn4, Rxn-10, Rxn-45, Rxn-46, bio multi optic and sleeve,
flow cell and flow bench, Raman optic system for single use) and
liquid analysis sensor technology and Liquid Analysis portfolio
(Liquiline CM44P, CM442 and OUSAF44, OUSBT66 and
Memosens CPS61E, CLS82E, COS81E, CLS82E).Language:
Czech
Version:
06/09/2024
File size:
381.4 KB
File name:
PU01584CEN_0124_cz_view.pdf
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-
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PU (Publication)
Prioritize scalability for an efficient biopharmaceutical product development lifecycle
This technical paper studies the importance of scalability as a
competitive advantage in bioprocessing in the Life Science industry,
and Endress+Hauser's scalable Raman systems (Raman Rxn2,
Raman Rxn4, Rxn-10, Rxn-45, Rxn-46, bio multi optic and sleeve,
flow cell and flow bench, Raman optic system for single use) and
liquid analysis sensor technology and Liquid Analysis portfolio
(Liquiline CM44P, CM442 and OUSAF44, OUSBT66 and
Memosens CPS61E, CLS82E, COS81E, CLS82E).Language:
English
Version:
27/06/2024
File size:
753.7 KB
File name:
PU01584CEN_0124.pdf
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PU (Publication)
発酵における高度なプロセスと 製品の制御 -ラボまたはプロセスにおける 組成分析用のラマン分光法
食品・飲料産業のバイオテクノロジーに適用されるラボやプロセスでの発酵組成分析のための、Kaiserラマンテクノロジーを搭載したラマン分光アナライ
ザーシステム（ラマンRxn2アナライザー、ラマンRxn4アナライザー、Rxn-10プローブ、Rxn-45プローブを含む）の概要.Language:
Japanese
Version:
02/08/2024
File size:
1.4 MB
File name:
PU01457CJA_0122_Adv_Process_Product_Control_Fermentations.pdf
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PU (Publication)
Lab-to-process monitoring & control in Life Sciences - Reliable measurement of bioprocess physical and chemical properties
A combined product list of analysis offerings from both Optical Analysis
and LIquid Analysis for bioprocessing applications in the life science
industry (including Raman Rxn2 analyzer, Raman Rxn4 analyzer,
Rxn-10 probe, bio multi optic and bio sleeve, Raman flow assembly,
Rxn-45 probe, Rxn-46 probe, Raman optic system for single use,
Memosens CPS61E, Memosens COS81E, OUSBT66, Memosens CPS61E,
Memosens CPS77E, Memosens CLS82E, OUSAF44, Memosens CPS11E,
Memosens CLS16E, TOC Analyzer CA79, Liquiline transmitter platform, and
Memobase software).Language:
English
Version:
11/04/2024
File size:
776.1 KB
File name:
PU01484CEN_0224.pdf
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-
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PU (Publication)
Endress+Hauser - your one-source Life Sciences technology partner
Graphic highlighting why Endress+Hauser is trusted by the
world's top biopharmaceutical manufacturers for its Life
Sciences expertise and reliable inline, real-time measurement
technologies like Raman spectroscopy systems (Raman Rxn2,
Raman Rxn4, Rxn-10, Rxn-45, Rxn-46, bio multi optic and sleeve,
flow cell and flow bench, Raman optic system for single use) and
liquid analysis sensor technology (Liquiline CM44P, CM442 and
OUSAF44, OUSBT66 and Memosens CPS61E, CLS82E, COS81E,
CLS82E).Language:
Czech
Version:
06/09/2024
File size:
353 KB
File name:
PU01585CEN_0124_cz_view.pdf
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Competence Brochure (CP)
Faster market entry, higher yields, and improved quality - Real-time, inline bioprocess monitoring and control from lab to GMP with Raman Rxn systems & Memosens digital sensors
This eBook highlights the Endress+Hauser inline analysis portfolio
for bioprocessing including Raman spectroscopy systems
(Raman Rxn2, Raman Rxn4, Rxn-10, Rxn-45, Rxn-46, bio multi optic
and sleeve, flow cell and flow bench, Raman optic system for single use)
and liquid analysis sensor technology (Liquiline CM44P, CM442 and
OUSAF44, OUSBT66 and Memosens CPS61E, CLS82E, COS81E, CLS82E)
in the Life Science industry.Language:
English
Version:
21/06/2024
File size:
1.9 MB
File name:
CP01579CEN_0124.pdf
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Competence Brochure (CP)
Faster market entry, higher yields, and improved quality - Real-time, inline bioprocess monitoring and control from lab to GMP with Raman Rxn systems & Memosens digital sensors
This eBook highlights the Endress+Hauser inline analysis portfolio
for bioprocessing including Raman spectroscopy systems
(Raman Rxn2, Raman Rxn4, Rxn-10, Rxn-45, Rxn-46, bio multi optic
and sleeve, flow cell and flow bench, Raman optic system for single use)
and liquid analysis sensor technology (Liquiline CM44P, CM442 and
OUSAF44, OUSBT66 and Memosens CPS61E, CLS82E, COS81E, CLS82E)
in the Life Science industry.Language:
Czech
Version:
06/09/2024
File size:
1.7 MB
File name:
CP01579CEN_0124_cz_view.pdf
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Competence Brochure (CP)
Raman spectroscopy food & beverage application guide - Trusted technology for composition analysis in a laboratory or process environment
A guide to Raman spectroscopy application notes for the
food & beverage industry (featuring studies using the
Raman Rxn2 analyzer, Raman Rxn4 analyzer, Rxn-10 probe,
Rxn-20 probe, Rxn-45 probe, and the immersion optic
and non-contact optic).Language:
English
Version:
17/02/2022
File size:
859 KB
File name:
CP01489CEN_0122.pdf
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Case Study (CS)
Raman upstream bioprocess control - Nicro provides turnkey solutions for fermenters
A case study that examines how Nicro used Raman spectroscopy
(including a Raman Rxn2 analyzer and a Raman Rxn-45 probe),
powered by Kaiser Raman technology, for advanced bioprocess
control in the life science industry.Language:
English
Version:
11/06/2024
File size:
2.4 MB
File name:
CS01903CEN_0124.pdf
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Case Study (CS)
Raman upstream bioprocess control - Nicro provides turnkey solutions for fermenters
A case study that examines how Nicro used Raman spectroscopy
(including a Raman Rxn2 analyzer and a Raman Rxn-45 probe),
powered by Kaiser Raman technology, for advanced bioprocess
control in the life science industry.Language:
Czech
Version:
06/09/2024
File size:
588.1 KB
File name:
CS01903CEN_0124_cz_view.pdf
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Innovation (IN)
Raman spectrographic probes - Robust optical measurement of chemical composition
An overview brochure about our Raman spectroscopy probe
portfolio including the Rxn-10 probe, Rxn-20 probe, Rxn-30 probe,
Rxn-40 probe, Rxn-41 probe, Rxn-45 probe, Rxn-46 probe, and
probe accessory optics (bIO-Optic, Raman single use optic system /
SUB, immersion optic , non-contact optic), powered by Kaiser Raman
technology.Language:
English
Version:
26/10/2021
File size:
4.9 MB
File name:
IN01225CEN_0121.pdf
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Innovation (IN)
Mesure optique robuste de la composition chimique
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Language:
French
Version:
16/03/2023
File size:
776 KB
File name:
IN01225CFR.pdf
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Innovation (IN)
ラマン分光プローブ - 堅牢な分光分析による化学組成分析
ラマン分光法プローブ製品ラインナップに関する概要パンフレットです。
この製品ラインナップには、Rxn-10プローブ、Rxn-20プローブ、Rxn-30プローブ、
Rxn-40プローブ、Rxn-41プローブ、Rxn-45プローブ、Rxn-46プローブ、
およびプローブオプティクアクセサリ（bIOオプティック、
シングルユース向けラマンオプティックシステム/SUB、浸漬オプティック、
非接触オプティック）が含まれています。
これらはすべて、Kaiserラマンテクノロジーによって動作します。Language:
Japanese
Version:
24/06/2024
File size:
5.4 MB
File name:
IN01225CJA_0121_Raman_spectroscopic_probes.pdf
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